Lower fructose intake may help protect against development of nonalcoholic fatty liver in adolescents with obesity

摘要: OBJECTIVES: Although obesity is a major risk factor for nonalcoholic fatty liver (NAFL), not all individuals with develop the condition, suggesting that other factors such as diet may also contribute to NAFL development. We evaluated associations between fructose and total sugar intake subsequent diagnosis of in adolescents without population-based cohort. METHODS: Adolescents participating Western Australian Pregnancy Cohort (Raine) Study completed 3-day food records body mass index measurement at age 14 years. At 17 years, participants underwent abdominal ultrasound determine status. Multivariable logistic regression models were used analyse energy-adjusted Food diaries assessments 592 adolescents. RESULTS: The prevalence was 12.8% group 50% obesity. Fructose did significantly differ or our cohort whole. Among obesity, those had lower years compared (mean ± standard deviation [SD] 38.8 19.8 g/day, vs 55.7 14.4 P = 0.02). Energy-adjusted independently associated (OR [odds ratio] 1.09, 95% CI 1.01-1.19, 0.03) after adjustment confounding factors. showed less significance 1.03, 0.999-1.07, 0.06). No significant observed categories. CONCLUSIONS: Lower consumption decreased rather than overall be more physiologically relevant this association.