Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
作者： Mark Sevecka , Olga Burenkova , Lin Nie , Gavin MacBeath
DOI:
关键词: Oncology 、 Cancer 、 Internal medicine 、 ERBB3 、 Cancer therapy 、 Medicine
摘要: Methods for predicting a therapeutic response in patient (e.g., cancer patient) to ErbB3 inhibitors, and methods of treating with targeted therapies.
lens.org 参考文章(353)
E. Peles, R. Ben-Levy, E. Tzahar, N. Liu, D. Wen, Y. Yarden, Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships. The EMBO Journal. ,vol. 12, pp. 961- 971 ,(1993) , 10.1002/J.1460-2075.1993.TB05737.X
Yoshihama Y, Matsumura T, Alcalde Re, Terakado N, Shintani S, Funayama T, Ootsuki K, Expression of c-erbB family gene products in adenoid cystic carcinoma of salivary glands: an immunohistochemical study. Anticancer Research. ,vol. 15, pp. 2623- 2626 ,(1995)
Drebin Ja, Link Vc, Greene Mi, Monoclonal antibodies reactive with distinct domains of the neu oncogene-encoded p185 molecule exert synergistic anti-tumor effects in vivo. Oncogene. ,vol. 2, pp. 273- ,(1988)
Nordenskjöld M, Werer G, Cruz J, Jimenez J, Collins P, Perez I, Franco S, Torroella M, Bäckdahl M, Zelada-Hedman M, High expression of the EGFR in fibroadenomas compared to breast carcinomas. Anticancer Research. ,vol. 14, pp. 1679- 1688 ,(1994)
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework* Clinical Pharmacology & Therapeutics. ,vol. 69, pp. 89- 95 ,(2001) , 10.1067/MCP.2001.113989
Sarah Bacus, Jason Hill, Targeted therapy marker panels ,(2005)
Eizo Kaneko, Tetsuro Oikawa, Akira Kono, Jiro Hitomi, Ken Yamaguchi, Frequent expression of genes for receptor tyrosine kinases and their ligands in human pancreatic cancer cells International Journal of Pancreatology. ,vol. 18, pp. 15- 23 ,(1995) , 10.1007/BF02825417
William Kubasek, Ashish Kalra, Rachel Nering, Navreet Dhindsa, Victor Moyo, Isabelle Tabah-Fisch, Joseph Pearlberg, Gavin Macbeath, Dosage and administration of anti-erbb3 antibodies in combination with paclitaxel ,(2012)
Hong-Hee Kim, Susan L Sierke, John G Koland, None, Epidermal growth factor-dependent association of phosphatidylinositol 3-kinase with the erbB3 gene product. Journal of Biological Chemistry. ,vol. 269, pp. 24747- 24755 ,(1994) , 10.1016/S0021-9258(17)31455-2
Lemoine Nr, Gullick Wj, Plowman Gd, Selden C, Prigent Sa, Hughes Cm, Expression of the c-erbB-3 protein in normal human adult and fetal tissues. Oncogene. ,vol. 7, pp. 1273- 1278 ,(1992)