Models in parasite and pathogen evolution: Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in parasitic protozoa, yeasts and bacteria.

作者: Francisco J. Ayala , Michel Tibayrenc

DOI: 10.1016/BS.APAR.2020.12.001

关键词: ProtozoaWhole genome sequencingMolecular epidemiologyMicroevolutionRange (biology)BiologyEvolutionary biologyPhylogenetic treeStrain (biology)Taxonomy (biology)

摘要: The predominant clonal evolution (PCE) model of pathogenic microorganisms postulates that the impact of genetic recombination in those pathogens' natural populations is not enough to erase a persistent phylogenetic signal at all evolutionary scales from microevolution till geological times in the whole ecogeographical range of the species considered. We have tested this model with a set of representative parasitic protozoa, yeasts and bacteria in the light of the most recent genomic data. All surveyed species, including …

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