作者: Marco A Cimmino , Massimiliano Parodi , Stefania Innocenti , Giulia Succio , Simone Banderali
DOI: 10.1186/AR1734
关键词: Synovitis 、 Dynamic contrast-enhanced MRI 、 Arthritis 、 Prospective cohort study 、 Magnetic resonance imaging 、 Nuclear medicine 、 Psoriatic arthritis 、 Medicine 、 Rheumatoid arthritis 、 Rheumatology 、 Internal medicine 、 Surgery
摘要: This dynamic magnetic resonance imaging (MRI) study is concerned with a prospective evaluation of wrist synovitis in patients psoriatic arthritis (PsA) comparison rheumatoid (RA) and healthy controls. Fifteen consecutive PsA, 49 RA, 30 RA matched for disease severity those 8 controls were studied. MRI was performed low-field (0.2T), extremity-dedicated machine. After an intravenous bolus injection gadolinium-diethylenetriaminepentaacetic acid, 20 fast spin-echo axial images the obtained every 18 s. The enhancement ratio calculated both as rate early (REE), which shows slope curve contrast uptake per second during first 55 s, relative (RE), indicates steady state enhancement. REE 1.0 ± 0.6 1.6 0.7 0.1 (p <0.001). RE 87.1 39.2 125.8 48.0 patients, 15.5 19.2 However, same figures 1.3 107.3 48.2, respectively (not significant PsA). Rheumatoid-like PsA oligoarticular did not differ from each other terms synovial Dynamic pattern when two groups are severity. technique cannot be used to differentiate RA. significantly higher than normal controls, only one instance overlap between values found groups.