Role of zinc supplementation in type II diabetes mellitus.

作者: C.B. Niewoehner , John I. Allen , Maria Boosalis , Allen S. Levine , John E. Morley

DOI: 10.1016/0002-9343(86)90183-X

关键词: Diabetes mellitusMedicineZinc deficiencyInsulinHemoglobinInternal medicineImmune systemCounts per minuteZincTasteEndocrinology

摘要: Zinc is required for normal immune function and taste acuity enhances the in vitro effectiveness of insulin. Impaired have been reported diabetic subjects, decreased serum zinc levels hyperzincuria occur some subjects animals. Subjects with type II diabetes were examined to determine whether similar effects depletion are causally related. Low found 16 180 (9 percent). There was no correlation between glycosylated hemoglobin levels. Natural killer cell activity did not differ (n = 28) control 38) correlate T lymphocyte response phytohemagglutinin lower than (70 +/- 10 versus 103 7 X 10(3) counts per minute) but lowest those Taste thresholds hydrochloric acid, sucrose, sodium chloride, urea elevated 10), or supplementation nine had effect on level, natural activity, thresholds, it increase mitogen initial responses. It concluded that deficiency occurs a subset related does explain acuity. may play role abnormal mellitus.

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