Preoperative Hip Injections Increase the Rate of Periprosthetic Infection After Total Hip Arthroplasty

作者: William W. Schairer , Benedict U. Nwachukwu , David J. Mayman , Stephen Lyman , Seth A. Jerabek

DOI: 10.1016/J.ARTH.2016.04.008

关键词: AmbulatoryMedicineOsteoarthritisRetrospective cohort studyAmbulatory Surgical ProcedureProsthesis-Related InfectionEpidemiologyPeriprostheticElective Surgical ProcedureSurgery

摘要: Abstract Background Intraarticular injections are both diagnostic and therapeutic for patients with osteoarthritis. A potential risk of periprosthetic joint infection (PJI) after total hip arthroplasty (THA) may occur from direct inoculation and/or immune suppression by corticosteroids. Large population-level databases were used to evaluate injection on the 1-year rate PJI in undergoing primary THA. Methods State-level ambulatory surgery inpatient Florida California (2005-2012) identify THA preoperative postoperative windows possible or PJI, respectively. Patients grouped as no performed 6-12 months, 3-6 0-3 months injection. Risk adjustment was multivariable regression. Results 173,958 included; 5421 (3.1%) underwent an injection: 1395 (1.1%) 1863 2163 (1.2%) months. In month group, significantly increased at 3 (1.58%, P  = .015), 6 (1.76%, .022), 1 year (2.04%, .031) compared noninjection control group (1.04%, 1.21%, 1.47%, respectively). There differences 3- 6-month 6- 12-month groups. Conclusion is when within We recommend that their surgeons consider delaying elective until avoid this elevated infection.

参考文章(31)
Peter Devane, Gordon Purdie, Andrew Davidson, Geoffrey Horne, Kathryn Adams, The influence of steroid injections on the incidence of infection following total knee arthroplasty. The New Zealand Medical Journal. ,vol. 121, ,(2008)
Brian C. Werner, Jourdan M. Cancienne, James A. Browne, The Timing of Total Hip Arthroplasty After Intraarticular Hip Injection Affects Postoperative Infection Risk Journal of Arthroplasty. ,vol. 31, pp. 820- 823 ,(2016) , 10.1016/J.ARTH.2015.08.032
Samuel E McMahon, Martyn E Lovell, Total hip arthroplasty after ipsilateral intra-articular steroid injection: 8 years follow up. Acta Orthopaedica Belgica. ,vol. 78, pp. 333- 336 ,(2012)
Javad Parvizi, Bahar Adeli, Benjamin Zmistowski, Camilo Restrepo, Alan Seth Greenwald, Management of periprosthetic joint infection: the current knowledge: AAOS exhibit selection. Journal of Bone and Joint Surgery, American Volume. ,vol. 94, pp. 104- ,(2012) , 10.2106/JBJS.K.01417
F Behrens, N Shepard, N Mitchell, Alterations of rabbit articular cartilage by intra-articular injections of glucocorticoids. Journal of Bone and Joint Surgery, American Volume. ,vol. 57, pp. 70- 76 ,(1975) , 10.2106/00004623-197557010-00012
Leelakrishna Nallamshetty, Jacob M. Buchowski, Levon A. Nazarian, Samridhi Narula, Monica Musto, Nicholas U. Ahn, Frank J. Frassica, Septic arthritis of the hip following cortisone injection: case report and review of the literature. Clinical Imaging. ,vol. 27, pp. 225- 228 ,(2003) , 10.1016/S0899-7071(02)00489-8
Amy L McIntosh, Arlen D Hanssen, Doris E Wenger, Douglas R Osmon, Recent intraarticular steroid injection may increase infection rates in primary THA. Clinical Orthopaedics and Related Research. ,vol. 451, pp. 50- 54 ,(2006) , 10.1097/01.BLO.0000229318.51254.79
Hilal Maradit Kremers, Laura W. Lewallen, Tad M. Mabry, Daniel J. Berry, Elie F. Berbari, Douglas R. Osmon, Diabetes mellitus, hyperglycemia, hemoglobin A1C and the risk of prosthetic joint infections in total hip and knee arthroplasty. Journal of Arthroplasty. ,vol. 30, pp. 439- 443 ,(2015) , 10.1016/J.ARTH.2014.10.009
Kevin J. Bozic, Edmund Lau, Steven Kurtz, Kevin Ong, Daniel J. Berry, Patient-related Risk Factors for Postoperative Mortality and Periprosthetic Joint Infection in Medicare Patients Undergoing TKA Clinical Orthopaedics and Related Research®. ,vol. 470, pp. 130- 137 ,(2012) , 10.1007/S11999-011-2043-3
Guy Maoz, Michael Phillips, Joseph Bosco, James Slover, Anna Stachel, Ifeoma Inneh, Richard Iorio, The Otto Aufranc Award: Modifiable versus Nonmodifiable Risk Factors for Infection After Hip Arthroplasty Clinical Orthopaedics and Related Research®. ,vol. 473, pp. 453- 459 ,(2015) , 10.1007/S11999-014-3780-X