Methodology for the study of metabolic syndrome by heart rate variability and insulin sensitivity
作者： Erika Severeyn , Sara Wong , Gianfranco Passariello , José Luis Cevallos , Deyanira Almeida
关键词: Cardiology 、 Heart rate variability 、 Group control 、 Insulin sensitivity 、 Diabetes mellitus 、 Ecg signal 、 Internal medicine 、 Oral glucose tolerance 、 Endocrinology 、 Medicine 、 Sympathetic tone 、 Metabolic syndrome
摘要: This work presents a methodology for studying the Heart Rate Variability (HRV) and Insulin Sensitivity (IS) during Oral Glucose Tolerance Test (OGTT) in subjects with Metabolic Syndrome (MS). For this, it was designed clinical protocol that includes acquisition of ECG signals OGTT 15 MS 10 control group. HRV parameters were obtained from electrocardiographic recordings. Significant differences RR values found between groups 30 minutes stage OGTT. In higher compared MS. The normalized low frequencies baseline stages at showed significant increase sympathetic tone OGTT, not observed group control. following methods implemented quantification IS: integral equation, insulin sensitivity index, sensitivity, metabolic, HOMA QUICKI. We significantly lower IS It concluded there are changes MS, which is pre-diabetic disease. These findings suggest can be used diagnosis prevention Diabetes Mellitus.
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