A haplotype of the CYP4F2 gene associated with myocardial infarction in Japanese men
作者： Zhenyan Fu , Tomohiro Nakayama , Naoyuki Sato , Yoichi Izumi , Yuji Kasamaki
DOI: 10.1016/J.YMGME.2008.11.161
关键词: Case-control study 、 Gene 、 CYP4F2 gene 、 Allele frequency 、 Single-nucleotide polymorphism 、 Haplotype 、 CYP4F2 、 Medicine 、 Myocardial infarction 、 Genetics
摘要: This study assessed associations between the CYP4F2 gene and myocardial infarction (MI), using a haplotype-based case-control of 234 MI patients 248 controls genotyped for 5 single-nucleotide polymorphisms (rs3093105, rs3093135, rs1558139, rs2108622, rs3093200). For men, G allele frequency rs2108622 T-C-G haplotype were significantly higher, T-C-A was lower than (P=0.006, P=0.001 P=0.002, respectively).
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