Method for preparing polymeric microspheres and polymeric microspheres produced thereby

作者: Hwang Yong-Youn , Oh Joon-Gyo , Um Key-An , Kim Hong-Kee , Lee Bong-Yong

DOI:

关键词: Chemical engineeringPolymerDispersion (chemistry)Drug deliverySolventEmulsionPolymeric microspheresPhase (matter)Mixing (process engineering)Materials science

摘要: The present invention relates to a method for preparing polymeric microspheres and produced thereby. More particularly, the microsphere comprising steps of: mixing water-insoluble organic solvent with dispersion solvent; polymer compound, drug so as prepare dispersed phase; phase mixed an emulsion; adding base or acid prepared emulsion remove from thereby, composition delivery microspheres. provides new preparation by removing water-insoluable solvents emulsions using acids, prepration method, Therefore, of is different original evaporation extraction procedures, realizes minimization waste water generation less water, simply prepares target durg-containing within short period.

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