作者: Hwang Yong-Youn , Oh Joon-Gyo , Um Key-An , Kim Hong-Kee , Lee Bong-Yong
DOI:
关键词: Chemical engineering 、 Polymer 、 Dispersion (chemistry) 、 Drug delivery 、 Solvent 、 Emulsion 、 Polymeric microspheres 、 Phase (matter) 、 Mixing (process engineering) 、 Materials science
摘要: The present invention relates to a method for preparing polymeric microspheres and produced thereby. More particularly, the microsphere comprising steps of: mixing water-insoluble organic solvent with dispersion solvent; polymer compound, drug so as prepare dispersed phase; phase mixed an emulsion; adding base or acid prepared emulsion remove from thereby, composition delivery microspheres. provides new preparation by removing water-insoluable solvents emulsions using acids, prepration method, Therefore, of is different original evaporation extraction procedures, realizes minimization waste water generation less water, simply prepares target durg-containing within short period.