Repression of translation of human estrogen receptor α by G-quadruplex formation
作者： Graham D. Balkwill , Kamila Derecka , Thomas P. Garner , Charlie Hodgman , Anthony P. F. Flint
DOI: 10.1021/BI901420K
关键词: Exon 、 Biology 、 Untranslated region 、 Messenger RNA 、 Gene 、 Estrogen receptor alpha 、 Estrogen receptor beta 、 Molecular biology 、 Transcription factor 、 Mutant
摘要: … spectroscopy that a stable DNA G-quadruplex motif is formed within … G-quadruplex motif is present in the 5′-UTR of the mRNA transcript, where it modulates the efficiency of translation…
acs.org
elsevier.com
sci-hub.se 参考文章(48)
RJ Weigel, EC deConinck, DL Crooks, JD Iglehart, Quantitative analysis of the transcriptional start sites of estrogen receptor in breast carcinoma. Cell Growth & Differentiation. ,vol. 6, pp. 707- 711 ,(1995)
Luigi Castagnetta, Emanuela Fecarotta, Ulrich Pfeffer, Giorgio Vidali, Estrogen receptor variant messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines Cancer Research. ,vol. 53, pp. 741- 743 ,(1993)
DNA Quadruplexes and Gene Regulation pp. 180- 207 ,(2006) , 10.1039/9781847555298-00180
Gilles Flouriot, Caroline Griffin, Maryrose Kenealy, Vera Sonntag-Buck, Frank Gannon, Differentially Expressed Messenger RNA Isoforms of the Human Estrogen Receptor-α Gene Are Generated by Alternative Splicing and Promoter Usage Molecular Endocrinology. ,vol. 12, pp. 1939- 1954 ,(1998) , 10.1210/MEND.12.12.0209
Jixun Dai, Thomas S. Dexheimer, Ding Chen, Megan Carver, Attila Ambrus, Roger A. Jones, Danzhou Yang, An Intramolecular G-Quadruplex Structure with Mixed Parallel/Antiparallel G-Strands Formed in the Human BCL-2 Promoter Region in Solution Journal of the American Chemical Society. ,vol. 128, pp. 1096- 1098 ,(2006) , 10.1021/JA055636A
Lech Zwierzchowski, Tomasz Szreder, Polymorphism within the bovine estrogen receptor- gene 5'-region Journal of Applied Genetics. ,vol. 45, pp. 225- 236 ,(2004)
Robert A. Heald, Chetna Modi, Jenny C. Cookson, Ian Hutchinson, Charles A. Laughton, Sharon M. Gowan, Lloyd R. Kelland, Malcolm F. G. Stevens, Antitumor Polycyclic Acridines. 8.1 Synthesis and Telomerase-Inhibitory Activity of Methylated Pentacyclic Acridinium Salts Journal of Medicinal Chemistry. ,vol. 45, pp. 590- 597 ,(2002) , 10.1021/JM011015Q
Pascale Hazel, Julian Huppert, Shankar Balasubramanian, Stephen Neidle, Loop-length-dependent folding of G-quadruplexes. Journal of the American Chemical Society. ,vol. 126, pp. 16405- 16415 ,(2004) , 10.1021/JA045154J
Letizia Penolazzi, Elisabetta Lambertini, Silvia Giordano, Vincenzo Sollazzo, Giancarlo Traina, Laura del Senno, Roberta Piva, Methylation analysis of the promoter F of estrogen receptor α gene: effects on the level of transcription on human osteoblastic cells The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 91, pp. 1- 9 ,(2004) , 10.1016/J.JSBMB.2004.02.005
Richard H. Shafer, Ivan Smirnov, Biological aspects of DNA/RNA quadruplexes Biopolymers. ,vol. 56, pp. 209- 227 ,(2000) , 10.1002/1097-0282(2000/2001)56:3<209::AID-BIP10018>3.0.CO;2-Y