A primary linkage map of the porcine genome reveals a low rate of genetic recombination.
作者： B P Chowdhary , M Fredholm , I Gustavsson , M Johansson , L Marklund
DOI: 10.1093/GENETICS/137.4.1089
关键词: Human genome 、 Gene mapping 、 Genetic linkage 、 Microsatellite 、 Genome size 、 Genetics 、 Biology 、 Genetic recombination 、 Genetic marker 、 Genome
摘要: A comprehensive genetic linkage map of the porcine genome has been developed by typing 128 markers in a cross between European Wild Boar and domestic breed (Large White). The marker set includes 68 polymerase chain reaction-formatted microsatellites, 60 anchored reference informative for comparative mapping 47 which have physically assigned situ hybridization. Novel multipoint assignments are provided 54 markers. covers about 1800 cM, average spacing is 11 cM. We used data to estimate size pigs, thereby addressing total recombination distance third mammalian species. sex-average length 1873 +/- 139 cM was obtained comparing recombinational physical distances defined regions genome. This strikingly different from human (3800-4000 cM) more similar mouse (1600 cM). rate females significantly higher than males.
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