Improving breast cancer therapy using doxorubicin loaded solid lipid nanoparticles: Synthesis of a novel arginine-glycine-aspartic tripeptide conjugated, pH sensitive lipid and evaluation of the nanomedicine in vitro and in vivo.
作者： Gang Zheng , Meizhu Zheng , Ben Yang , Hui Fu , Yongqing Li
DOI: 10.1016/J.BIOPHA.2019.109006
关键词: Solid lipid nanoparticle 、 In vitro 、 Pharmacology 、 Cmax 、 Doxorubicin 、 Breast cancer 、 Adipic acid dihydrazide 、 Chemistry 、 Tripeptide 、 In vivo
摘要: … , an arginine-glycine-aspartic (RGD) tripeptide modified, pH-sensitive solid lipid nanoparticles (SLNs) is employed in this study. In this study, a RGD conjugated, pH sensitive lipid was …
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