Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma
作者： Anxun Wang , Xiqiang Liu , Shihu Sheng , Hui Ye , Tingsheng Peng
关键词: Surgical oncology 、 Oncology 、 Basal cell 、 Internal medicine 、 Tongue SCC 、 Stem cell 、 Heat shock protein 、 Medicine 、 Hsp27 、 Tongue squamous cell carcinoma 、 Tongue Neoplasm
摘要: Background Recent proteomic studies identified Hsp27 as a highly over-expressed protein in oral squamous cell carcinoma (OSCC). Clinical that attempted to evaluate the prognostic values of yielded inconsistent results, which may be due inclusion OSCC cases from multiple anatomic sites. In this study, determine utility for prognosis, we focused on tongue SCC (OTSCC), one most aggressive forms OSCC.
biomedcentral.com
springer.com
core.ac.uk
paperity.org参考文章(39)
Francesco Carinci, Giuseppina Campisi, Silvia Falaschini, Lorenzo Lo Muzio, Antonio Farina, Gaetano De Rosa, Rosalia Leonardi, Corrado Rubini, Stefania Stalbano, Francesca Ferrari, Prognostic Value of HSP27 in Head and Neck Squamous Cell Carcinoma: a Retrospective Analysis of 57 Tumours Anticancer Research. ,vol. 26, pp. 1343- 1349 ,(2006)
Piura B, Yavelsky, Rabinovich A, Wolfson M, Heat shock proteins and malignancies of the female genital tract Harefuah. ,vol. 141, pp. 969- 1009 ,(2002)
John P. Neoptolemos, Keith F. Parsons, Anthony D. Desmond, Alan Woolfenden, Youqiang Ke, Mark Fordham, Andrew R. Dodson, Christopher S. Foster, Philip A. Cornford, Heat shock protein expression independently predicts clinical outcome in prostate cancer. Cancer Research. ,vol. 60, pp. 7099- 7105 ,(2000)
Lajos D�br�ssy, Epidemiology of head and neck cancer: magnitude of the problem. Cancer and Metastasis Reviews. ,vol. 24, pp. 9- 17 ,(2005) , 10.1007/S10555-005-5044-4
S. Oesterreich, C. K. Osborne, S. A. W. Fuqua, Ming Qiu, S. G. Hilsenbeck, Chye-Ning Weng, The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines Cancer Research. ,vol. 53, pp. 4443- 4448 ,(1993)
P. Mehlen, C. Kretz-Remy, X. Préville, A. P. Arrigo, Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death The EMBO Journal. ,vol. 15, pp. 2695- 2706 ,(1996) , 10.1002/J.1460-2075.1996.TB00630.X
L Xu, S Chen, R C Bergan, MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer. Oncogene. ,vol. 25, pp. 2987- 2998 ,(2006) , 10.1038/SJ.ONC.1209337
Kuang-Liang King, Anna F-Y Li, Gar-Yang Chau, Chin-Wen Chi, Chew-Wun Wu, Chen-Lung Huang, Wing-Yiu Lui, Prognostic significance of heat shock protein-27 expression in hepatocellular carcinoma and its relation to histologic grading and survival. Cancer. ,vol. 88, pp. 2464- 2470 ,(2000) , 10.1002/1097-0142(20000601)88:11<2464::AID-CNCR6>3.0.CO;2-W
John Rouse, Philip Cohen, Sylviane Trigon, Michel Morange, Ana Alonso-Llamazares, Daniel Zamanillo, Tim Hunt, Angel R. Nebreda, A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. ,vol. 78, pp. 1027- 1037 ,(1994) , 10.1016/0092-8674(94)90277-1
J�zsef T�m�r, Orsolya Csuka, �va Remen�r, G�bor R�p�ssy, Mikl�s K�sler, Progression of head and neck squamous cell cancer. Cancer and Metastasis Reviews. ,vol. 24, pp. 107- 127 ,(2005) , 10.1007/S10555-005-5051-5