Systemic thromboembolism in mitral and aortic Starr-Edwards prostheses: a 10-19 year follow-up.

摘要: Our study comprised 302 consecutive patients seen between 1962 and 1971 who underwent mitral (MVR) (132 patients) or aortic valve replacement (AVR) (170 with a Starr-Edwards prosthesis because of advanced incompetence. The follow-up interval was 10-19 years. For more recent models (1200/1260 6120/6310 mitral), the probability surviving patient remaining free systemic thromboembolism after 10 years 70% for MVR 74% AVR. freedom from less than this earlier models; entire group at 66% 15 58%, no significant difference AVR MVR. About one-fourth an embolism (20% MVR, 27% AVR) had one embolic event. Of all emboli, most (86% 84% were cerebral, about half (48% 57% left neurologic deficit, one-tenth (11% 10% led to death. predictive factors reviewed, incidence emboli significantly higher only in considered have inadequate anticoagulation (p 0.01) receiving model 6000 0.02). This long-term reveals that is persistent problem.