Quantitative EEG in patients with alcohol-related seizures.

作者: Trond Sand , Marte Bjørk , Geir Bråthen , Ralf P. Michler , Eylert Brodtkorb

DOI: 10.1111/J.1530-0277.2010.01262.X

关键词: Neurological disorderAudiologyElectroencephalographyWakefulnessConvulsionAlcohol Use Disorders Identification TestPsychologyQuantitative electroencephalographyCentral nervous system diseaseEpilepsyAnesthesia

摘要: Background:  To investigate whether quantitative electroencephalography (QEEG) recorded within a few days after generalized seizure can improve the discrimination between alcohol-related seizures (ARSs), in epilepsy and other seizures. In addition, we wanted to evaluate influence of various external factors on QEEG, e.g., drug use, time from occurrence, alcohol intake. Methods:  An ARS was defined by (i) scores ≥8 Alcohol Use Disorders Identification Test (AUDIT) (ii) no history epilepsy. Twenty-two patients, 21 epileptic patients with (ES), 30 AUDIT-negative (OS), 37 well-controlled outpatients (EPO) were included. EEG 79 sciatica (SC) served as an additional control group. relaxed wakefulness eyes closed. Spectral analysis ongoing resting activity performed. For main analysis, spectral band amplitudes averaged across 14 electrodes. Results:  Major abnormalities mainly seen ES AUDIT score correlated negatively QEEG unrelated alcohol, but not Recent intake delta theta amplitude. We could confirm that beta is increased subjects. Conclusions:  A slightly reduced alpha amplitude supports clinical diagnosis ARS. abnormally slow profile asymmetry temporal regions indicates ES. predicted better than standard EEG.

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