The different infectivity of Trichinella spiralis and Trichinella nativa in rat does not solely localize to enteral or parenteral phase.

摘要: Rats are selective hosts for Trichinella nativa; infection levels in their muscles remain low when compared to spiralis. To identify which phase of the life cycle responses take place, rats were infected perorally (p.o.) and intravenously (i.v.) with T. spiralis nativa. Six placed each group; three served as uninfected controls. The intensities examined 5 or 6 weeks after infection. muscle larva burden was 57 times higher that nativa p.o. inoculation (mean larvae per gram ± SD, 1,243 378.9 vs. 22 21.5). In i.v. inoculation, 12 more reached than Also, vitro newborn (NBL) production at day postinfection analyzed parasites originating from both rat mouse. mean number vitro-produced NBL rat-origin during 24 h 70 (95 % CI, 65–75) nativa, 23 21–24). Intriguingly, this difference less obvious mouse-origin female Trichinella. mouse origin 51–62) 29 26–31). Intestine histology 40 post infection, serological response, weight dynamics indistinguishable between species but differed Our results show defense against is not solely enteral may partly be explained by different reproduction processes two rat.