Increasing rates of Salmonella Paratyphi A and the current status of its vaccine development.

摘要: Enteric fever caused by Salmonella enterica serovar Typhi and Paratyphi is still a major disease burden mainly in developing countries. Previously, S. was believed to be the cause of enteric fever. The real situation now becoming clear with reports emerging from many Asian countries Paratyphi, mostly A, causing substantial number cases Although there have been advances use currently available typhoid vaccines development newer vaccines, paratyphoid vaccine lagging behind. Since are clinically indistinguishable commonly termed 'enteric' fever, it will necessary against both A as bivalent 'enteric vaccine'.