Identification of 2′-Fucosyllactose in Milk of the Crabeater Seal (Lobodon carcinophagus)

作者: Tadasu Urashima , Yoriko Hiramatsu , Sachiko Murata , Tadashi Nakamura , Michael Messer

DOI: 10.1016/S0305-0491(96)00209-X

关键词: Paper chromatographyLobodon carcinophagusSeal (mechanical)LactoseChromatographyOligosaccharide2'-FucosyllactoseFucoseChemistry

摘要: Abstract 1. An oligosaccharide was isolated from extracts of crabeater seal milk by preparative paper chromatography. 2. The saccharide identified as Fuc α 1–2Ga1 β 1–4G1c 1 H-NMR spectroscopy. 3. This work represents the first identification an oligosaccharide, other than lactose, in a pinniped.

参考文章(16)
K.R Kerry, M Messer, Intestinal glycosidases of three species of seals Comparative Biochemistry and Physiology. ,vol. 25, pp. 437- 446 ,(1968) , 10.1016/0010-406X(68)90352-6
John D. Johnson, Robert O. Christiansen, Norman Kretchmer, Lactose synthetase in mammary gland of the California sea lion Biochemical and Biophysical Research Communications. ,vol. 47, pp. 393- 397 ,(1972) , 10.1016/0006-291X(72)90726-7
M. Messer, K. R. Kerry, Milk Carbohydrates of the Echidna and the Platypus Science. ,vol. 180, pp. 201- 203 ,(1973) , 10.1126/SCIENCE.180.4082.201
Richard Kuhn, Hans Helmut Baer, Adeline Gauhe, Fucosido‐lactose, das Trisaccharid der Frauenmilch Chemische Berichte. ,vol. 88, pp. 1135- 1146 ,(1955) , 10.1002/CBER.19550880802
Robert Jenness, Edna A. Regehr, Robert E. Sloan, Comparative biochemical studies of milks— II. Dialyzable carbohydrates Comparative Biochemistry and Physiology. ,vol. 13, pp. 339- 352 ,(1964) , 10.1016/0010-406X(64)90028-3
J. E. Hodge, Determination of reducing sugars and carbohydrates Methods in carbohydrate chemistry. ,vol. 1, pp. 380- 394 ,(1962)
Norman Kretchmer, Philip Sunshine, Intestinal disaccharidase deficiency in the sea lion. Gastroenterology. ,vol. 53, pp. 123- 129 ,(1967) , 10.1016/S0016-5085(19)34272-6
Olav T. Oftedal, Daryl J. Boness, Raymond A. Tedman, The Behavior, Physiology, and Anatomy of Lactation in the Pinnipedia Current mammalogy. ,vol. 1, pp. 175- 245 ,(1987) , 10.1007/978-1-4757-9909-5_6