Glucuronic acid derivatives of opioid antagonists
作者： Ronald R. Tuttle , Ross Dixon , Maciej M. Smulkowski
DOI:
关键词: Antagonist 、 Glucuronide 、 Opioid antagonist 、 Chemistry 、 Opioid 、 Glucuronic acid 、 Central nervous system 、 Pharmacology
摘要: Intestine-specific delivery of an opioid antagonist can be accomplished without substantial central nervous system effects by administering the orally in form glucuronide derivative.
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