Study of vascular injuries using endothelial denudation model and the therapeutic application of shock wave: a review.

作者: Cheuk-Kwan Sun , Hon-Kan Yip , Pei-Lin Shao , Ching-Jen Wang

DOI:

关键词: AngiogenesisBioinformaticsTreatment resultsMedicineBalloon catheterEndothelial denudationDeath tollDisease mechanismsDisease progressionAnimal model

摘要: As death toll from cardiovascular diseases has reached historic heights in the developed world, research efforts have been focused on both understanding of disease progression and also choice appropriate treatment strategies. Moreover, to facilitate research, an animal model is needed mimic pathological changes follow results. This article reviewed mechanisms underlying vascular injuries endothelial denudation using balloon catheter. On other hand, biological effects shock wave including angiogenesis suppression inflammation were reviewed. Its therapeutic impact system its potential clinical application as well limitations discussed.

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