The effect of pH on transformation of BHK21 cells by polyoma virus
作者： Alexander L. Kisch , Kenneth B. Fraser
DOI: 10.1016/0042-6822(64)90102-3
关键词: Virus 、 Hamster 、 Tissue culture 、 Antigen 、 Biology 、 Transformation (genetics) 、 Staining 、 Fibroblast 、 Molecular biology 、 Biochemistry 、 Cell division 、 Virology
摘要: Abstract The frequency with which BHK21 hamster fibroblast cells undergo transformation after infection by polyoma virus (PV) was studied as a function of pH at cultures were incubated following the adsorption virus. rate (t col) highest values between 7.6 and 7.8 lowest 7.0 below. This phenomenon appeared to be directly related rather than bicarbonate ion concentration independent secondary selective processes. change in percentage infected synthesized nuclear viral antigen detectable immunofluorescent staining not same underwent varied.
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sci-hub.se 参考文章(22)
C.P. Stanners, J.E. Till, L. Siminovitch, STUDIES ON THE TRANSFORMATION OF HAMSTER EMBRYO CELLS IN CULTURE BY POLYOMA VIRUS. I. PROPERTIES OF TRANSFORMED AND NORMAL CELLS. Virology. ,vol. 21, pp. 448- 463 ,(1963) , 10.1016/0042-6822(63)90206-X
L.V. Crawford, E.M. Crawford, D.H. Watson, The physical characteristics of polyoma virus. I. Two types of particle. Virology. ,vol. 18, pp. 170- 176 ,(1963) , 10.1016/0042-6822(62)90002-8
Sophie Leventon, Tamar Gotlieb-Stematsky, Studies on the biological properties of two plaque variants isolated from SE polyoma virus. British journal of experimental pathology. ,vol. 41, pp. 507- 519 ,(1960)
M. S. Bartlett, Properties of Sufficiency and Statistical Tests Proceedings of The Royal Society A: Mathematical, Physical and Engineering Sciences. ,vol. 160, pp. 268- 282 ,(1992) , 10.1007/978-1-4612-0919-5_8
Ian Macpherson, Michael Stoker, Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence. Virology. ,vol. 16, pp. 147- 151 ,(1962) , 10.1016/0042-6822(62)90290-8
Michael Stoker, Delayed transformation by polyoma virus. Virology. ,vol. 20, pp. 366- 371 ,(1963) , 10.1016/0042-6822(63)90126-0
D.C. Stuart, Jørgen Fogh, Micromorphology of FL cells infected with polio and Coxsackie viruses Virology. ,vol. 13, pp. 177- 190 ,(1961) , 10.1016/0042-6822(61)90052-6
E. A. McCULLOCH, A. F. HOWATSON, L. SIMINOVITCH, A. A. AXELRAD, A. W. HAM, A cytopathogenic agent from a mammary tumour in a C3H mouse that produces tumours in Swiss mice and hamsters. Nature. ,vol. 183, pp. 1535- 1536 ,(1959) , 10.1038/1831535A0
K.B. Fraser, Meera Gharpure, Immunofluorescent tracing of polyoma virus in transformation experiments with BHK 21 cells Virology. ,vol. 18, pp. 505- 507 ,(1962) , 10.1016/0042-6822(62)90048-X
J.D. Smith, G. Freeman, M. Vogt, R. Dulbecco, The nucleic acid of polyoma virus Virology. ,vol. 12, pp. 185- 196 ,(1960) , 10.1016/0042-6822(60)90193-8