IMMUNOFLUORESCENT AND ELECTRON-MICROSCOPIC STUDIES OF POLYOMA VIRUS IN TRANSFORMATION REACTIONS WITH BHK21 CELLS.
作者： K.B. Fraser , Elizabeth M. Crawford
DOI: 10.1016/0014-4800(65)90023-7
关键词:
摘要: Abstract When exposed to polyoma virus in transformation experiments, BHK21 cells may be shown, by immunofluorescent tracing, have adsorbed and ingested rapidly; retained it mostly cytoplasmic vacuoles; transmitted daughter for at least six successive mitoses. Electron microscopy recovery of virus-hemagglutinin supported these conclusions. Ingested was not seen cell nuclei. Three days after infection, new antigen appeared a small proportion nuclei, increased amount, spread the cytoplasm cells. Similar observations were made colonies arising from individual polyoma-infected Data are insufficient establish any relationship between synthesis transformation.
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