摘要: Abstract When single BHK21 cells exposed to polyoma virus were isolated in microdrops they gave rise normal, transformed, and mixed clones. Mixed clones constituted more than one-third of the total with transformed cells, when recloned pure cultures normal cells. propagated without recloning, rapidly replaced are probably due delayed transformation occurring up 7 or 8 generations after exposure cell virus. This late may be persistence intact some part it dividing
sci-hub.se 参考文章(9)
A Serum-Free Nutrient Solution Sustaining Rapid and Continuous Proliferation of Strain L (Earle) Mouse Cells Journal of the National Cancer Institute. ,vol. 17, pp. 315- 327 ,(1956) , 10.1093/JNCI/17.3.315
Ian Macpherson, Michael Stoker, Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence. Virology. ,vol. 16, pp. 147- 151 ,(1962) , 10.1016/0042-6822(62)90290-8
K.B. Fraser, Meera Gharpure, Immunofluorescent tracing of polyoma virus in transformation experiments with BHK 21 cells Virology. ,vol. 18, pp. 505- 507 ,(1962) , 10.1016/0042-6822(62)90048-X
Michael Stoker, Ian MacPherson, Studies on transformation of hamster cells by polyoma virus in vitro Virology. ,vol. 14, pp. 359- 370 ,(1961) , 10.1016/0042-6822(61)90320-8
Michael Stoker, Characteristics of normal and transformed clones arising from BHK21 cells exposed to polyoma virus. Virology. ,vol. 18, pp. 649- 651 ,(1962) , 10.1016/0042-6822(62)90071-5
A. Lwoff, R. Dulbecco, Marguerite Vogt, Marguerite Lwoff, Kinetics of the release of poliomyelitis virus from single cells. Virology. ,vol. 1, pp. 128- 139 ,(1955) , 10.1016/0042-6822(55)90010-6
PETER WILDY, MICHAEL STOKER, Multiplication of solitary HeLa cells. Nature. ,vol. 181, pp. 1407- 1408 ,(1958) , 10.1038/1811407A0
L.V. Crawford, The adsorption of polyoma virus. Virology. ,vol. 18, pp. 177- 181 ,(1962) , 10.1016/0042-6822(62)90003-X
M. Stoker, P. Abel, Conditions Affecting Transformation by Polyoma Virus Cold Spring Harbor Symposia on Quantitative Biology. ,vol. 27, pp. 375- 386 ,(1962) , 10.1101/SQB.1962.027.001.035