Excitotoxicity in neurological diseases : new therapeutic challenge

摘要: and historical notes.- I: Basic mechanisms.- 1. Contribution of astrocyte glutamate release to excitotoxicity.- 2. Glutamate uptake transporters.- 3. NMDA receptors.- 4. AMPA receptor synaptic plasticity.- 5. Metabotropic receptors neurodegeneration.- 6. Mechanisms excitotoxicity excitoprotection.- II: Acute chronic neurological disorders.- 7. Epilepsy seizures: or excitotrophicity?.- 8. Excitotoxicity in cerebral ischemia.- 9. traumatic brain injury.- 10. amyotrophic lateral sclerosis: selective vulnerability motor neurons.- 11. transmission the pathogenesis Parkinson's disease.- 12. Huntington's Disease.- 13. The glutamatergic system Alzheimer's disease brain: dysfunction associated with amyloid ?-peptide oxidative stress.- 14. Neurotoxicity prion 15. multiple sclerosis.- 16. HIV-1 dementia.- 17. Markers patients: tool for diagnosis therapy?.- 18. Anti-excitotoxic therapies diseases: current evidences new perspectives.