Characterization of pathologic complete response after preoperative chemoradiotherapy in carcinoma of the esophagus and outcome after pathologic complete response
作者： Pooja Rohatgi , Stephen G. Swisher , Arlene M. Correa , Tsung-T. Wu , Zhongxing Liao
DOI: 10.1002/CNCR.21439
关键词: Primary tumor 、 Carcinoma 、 Radiation therapy 、 Esophagus 、 Surgery 、 Chemoradiotherapy 、 Induction chemotherapy 、 Medicine 、 Esophageal disease 、 Gastroenterology 、 Stage (cooking) 、 Internal medicine
摘要: BACKGROUND
The purpose of the current study was to test hypothesis that a lower clinical TNM stage is associated with higher rate pathologic complete response (pathCR) in patients esophageal carcinoma receiving preoperative chemoradiotherapy and determine whether outcome after pathCR related or treatment.
METHODS
Clinical parameters surgical specimens undergoing were analyzed identify predictors pathCR. In pathCR, overall survival (OS), disease-free (DFS), distant recurrence studied.
RESULTS
Sixty-nine (29%) 235 achieved American Joint Committee on Cancer (AJCC) Stage II carcinoma, proportion achieving significantly larger than
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