作者: Duriasz-Rowińska H , Rylski M , Rewerski W
DOI:
关键词: Threshold of pain 、 Hyperoside 、 Analgesic 、 Chemistry 、 Pharmacology 、 Quercetin 、 Vitexin rhamnoside 、 Hot plate test 、 Male mice 、 Rutin
摘要: Albino-Swiss male mice were tested in the hot plate test. Oligomeric procyjanidin (OL-1), rutin, quercetin, hyperoside and vitexin rhamnoside administered intraperitoneally doses 3.5 10 mg/kg. It was found that OL-1, rutin but not exert analgesic action, whereas quercetin even decreases pain threshold level. The mechanism of action flavonoids remains to be explained.