The analgesic action of some flavonoids in the hot plate test.

作者: Duriasz-Rowińska H , Rylski M , Rewerski W

DOI:

关键词: Threshold of painHyperosideAnalgesicChemistryPharmacologyQuercetinVitexin rhamnosideHot plate testMale miceRutin

摘要: Albino-Swiss male mice were tested in the hot plate test. Oligomeric procyjanidin (OL-1), rutin, quercetin, hyperoside and vitexin rhamnoside administered intraperitoneally doses 3.5 10 mg/kg. It was found that OL-1, rutin but not exert analgesic action, whereas quercetin even decreases pain threshold level. The mechanism of action flavonoids remains to be explained.

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