Method validation and measurement uncertainty of possible thirty volatile organic compounds (VOCs) presented in the polyethylene present in bottled drinking waters sold in Turkey

摘要: This study was actualized for the simultaneous determination of possible thirty VOCs presented in drinking waters Turkey by direct injection to purge and trap (PT) gas chromatography-mass spectrometry (GC-MS). It consists selectivity, linearity, limit detection (LOD) quantification (LOQ), accuracy (recovery), precision, trueness, measurement uncertainty studies. In values correlation coefficients (r2) matrix-matched calibration curves were higher than 0.998 all analytes. method showed high sensitivity (LOD: 0.011–0.040 μg/L; LOQ: 0.035–0.133 μg/L), quite sufficient recovery (82.6% 103.1%) accuracy, acceptable precision (intra-day recovery: 81.5–104.4%, relative standard deviation (RSD): 1.04–9.81%; inter-day 92.6–104.1%, RSD: 1.15–7.52%). All RSD obtained below 10% are evaluated agreeable point AOAC EURACHEM/CITAC validation guidelines. The percentages analytes CRM changed between 80.3 109.9% (%) each analyte 10%. proficiency test results satisfactory comparable (z score less or equal 2.0 is no questionable satisfactory) those other laboratories participating round. calculated percentage uncertainties from 2.99 10.10% major contribution budget arises curve repeatability. Therefore, demonstrate that this applicable routine analysis custom laboratories.