Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation.
作者： A Lopergolo , M Pennati , P Gandellini , N I Orlotti , P Poma
关键词: Biology 、 Programmed cell death 、 RNA interference 、 Gene silencing 、 Apoptosis 、 Cell growth 、 Small interfering RNA 、 Caspase 3 、 Cancer research 、 Gene knockdown
摘要: … that p53 stabilisation and caspase-3 activation concur to determine the apoptotic response … To confirm this, we assessed by western blot the total amount of p53 after Apollon silencing …
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