Facilitation reaction (enhancing antibodies and suppressor cells) and rejection reaction (sensitized cells) from the mother to the paternal antigens of the conceptus.

摘要: Humoral and cellular immune agents of a maternal reaction were investigated during pregnancy. Fluorescence studies performed on mouse placentae at 14 days detected immunoglobulins mainly IgG1 but also IgG2 subclasses. These immunoglobulins, after acid elution, can rebind the placenta thymocytes relevant paternal strain in case allogeneic pregnancies, demonstrating an antibody activity towards both specific antigens. They specifically enhance tumour allograft recipient. Spleen cells from allogeneically pregnant mother reduce or promote The aggressive effect is shown with small doses transferred cells, whereas large enhancement. suppression cytotoxic response recipient was ascribed to T by use anti-theta plus complement. Thus, rejection (immune cells) facilitation (enhancing antibodies suppressor demonstrated