Antiphospholipid antibody syndrome in childhood strokes
作者： Jun-ichi Takanashi , Katsuo Sugita , Suzuko Miyazato , Eiko Sakao , Haruko Miyamoto
DOI: 10.1016/0887-8994(95)00218-9
关键词: Magnetic resonance angiography 、 Stroke 、 Lupus anticoagulant 、 Pathology 、 Infarction 、 Central nervous system disease 、 Moyamoya disease 、 Internal medicine 、 Vascular disease 、 Magnetic resonance imaging 、 Cardiology 、 Medicine
摘要: The significance of antiphospholipid antibodies was examined in patients with childhood strokes. Eight patients, aged 2-13 years, who presented acute hemiplegia were studied. On the basis magnetic resonance imaging, angiography, single photon emission computed tomography, and cerebral angiographic findings, 3 children diagnosed as having infarctions due to moyamoya disease, others idiopathic infarctions. Serologic studies revealed elevated anticardiolipin antibody (ACA) IgG 5 infarction; no such elevation disease. Values for all other tests, including ACA IgM lupus anticoagulant, within normal limits or negative patients. IgG, therefore, may be a more important causative agent strokes than previously considered.
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