Genetic variation in interleukin 8 and its receptor genes and its influence on the risk and prognosis of prostate cancer among Finnish men in a large cancer prevention trial
作者： Hannah P. Yang , Karen Woodson , Philip R. Taylor , Pirjo Pietinen , Demetrius Albanes
DOI: 10.1097/01.CEJ.0000199504.07947.E7
关键词: Genetic variation 、 Pathogenesis 、 Angiogenesis 、 Cytokine 、 Interleukin 8 、 Oncology 、 Internal medicine 、 Immune system 、 Cancer Prevention Trial 、 Medicine 、 Prostate cancer
摘要: The cytokine interleukin 8 (IL-8) may play a role in the pathogenesis of prostate cancer through modulation tumour immune response or enhanced angiogenesis. A common polymorphism IL-8 (–251) gene, which affect production level cytokine, has been inversely associated with
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