AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome

作者: Neil Ruderman , Marc Prentki

DOI: 10.1038/NRD1344

关键词: Type 2 diabetesInsulin resistanceSignal transductionAMPKMedicineAdenylate kinaseMetabolic syndromeEndocrinologyProtein kinase AMalonyl Coenzyme AInternal medicine

摘要: … activity and/or increased malonyl-CoA levels in insulin-… AMPK and possibly reduce malonyl-CoA levels, including … and/or reduce malonyl-CoA indicate that the AMPK/malonyl-CoA …

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