REMOVAL OF NEUROBLASTOMA CELLS FROM BONE MARROW WITH MONOCLONAL ANTIBODIES CONJUGATED TO MAGNETIC MICROSPHERES

作者: J.G Treleaven , J Ugelstad , T Philip , F.M Gibson , A Rembaum

DOI: 10.1016/S0140-6736(84)90004-7

关键词:

摘要: Abstract Monoclonal anibodies bound to polystyrene microspheres containing magnetite have been used remove tumour cells from bone marrow destined for autologous transplantation. The small magnetic beads can be targeted the surface of render these magnetic. A flow system using permanent samarium cobalt magnets effects rapid and efficient removal "magnetic" marrow. is designed with any type cell, so that by changing panels monoclonal antibody it "cleaning" in many different malignancies.

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