Human tumor antigens.

摘要: Publisher Summary This chapter focuses mainly on those human tumor antigens defined by using murine Mabs as molecular and functional probes. Particular emphasis has been placed describing glycoprotein ganglioside that serve targets for cancer therapy biochemically cellular markers ultimately delineating basic mechanisms of invasion metastasis. Large numbers glycoproteins have targeted potential tumor-associated antigens, essentially because the relative ease which such can be produced. The vast majority these not characterized in depth to their characteristics. On contrary, major thrust efforts determine directed diagnosis monitoring cancer. Researchers described immunochemical characterization four melanoma-associated antigens. These antibodies were expressed antigenic structures associated with p2-microglobulin or histocompatibility findings are agreement previous results polyclonal alloantisera xenoantisera, respectively, show serologically detectable Several key studies discussed development focus is examined some roles markers.