Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I'm-Yunity (PSP).

摘要: Background I'm-Yunity™ (PSP) is a mushroom extract derived from deep-layer cultivated mycelia of the patented Cov-1 strain Coriolus versicolor (CV), which contains as its main bioactive ingredient family polysaccharo-peptide with heterogeneous charge properties and molecular sizes. I'm-Yunity™ used dietary supplement by cancer patients individuals diagnosed various chronic diseases. Laboratory studies have shown that enhances immune functions also modulates cellular responses to external challenges. Recently, was reported exert potent anti-tumorigenic effects, evident suppression cell proliferation induction apoptosis in malignant cells. We investigate mechanisms elicits these effects.