Synthese und Konfigurationsbestimmung diastereomerer 9‐Methylcarbazole
作者： Lübomir D. Zheljazkov , Kitschka Faitondjieva , Milka Dimitrova , Stefan L. Spassov , Mariana Palamareva
DOI: 10.1002/JLAC.197919790203
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摘要: Es wurden Reformatsky- und Curtius-Reaktionen von Carbazol-Derivaten untersucht, wobei mit guten Ausbeuten diastereomere s-Hydroxydrazide, 4a b, Oxyzolidone 6a b 8c-e,s -Aminoalkohole 7a-e wie auch einige verwandte Verbindungen erhalten wurden. Die Konfigurationen 1a, einer dunnschichtchromatographischen Methode be-stimmt. Konfiguration Konformation der Diastereomeren .1H-NMR- IR-spektroskopisch ermittelt. Synthesis and Configuration of Diastereomeric 9-Methylcarbazole Compounds A synthetic route including Reformatsky Curtius reactions has been used for the preparation diastereomeric s-hydroxyesters hydroxyhydrazides 4a, oxazolidones 6a, 8c-e, amino alcohols 7a -e some related compounds in good yields. The relative configurations have determined by a thin-layer chromatographic method. configuration conformation carbazole derivatives studied by1H-NMR IR spectroscopy.
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