Comparative effects of four legume species on plasma lipids and faecal steroid excretion in hypercholesterolaemic pigs.

摘要: The effect of four species legume seeds on plasma cholesterol levels and faecal steroid excretion was studied in pigs. Thirty-six growing boars were randomly allocated groups six to diets which they ate continuously for 42 d. fed were: 1, a semi-purified (SP; control group 1) diet; 2, SP 10 g cholesterol/kg (control 2); 3, 4, 5, 6, + cooked legumes (70:30, w/w; respectively baked beans (Phaseolus vulgaris), peas (Pisum sativum), lentils (Lens culinaris Medik.), butter lunatus)) cholesterol/kg. Fasting blood samples taken days 0, 14, 28, the determination total cholesterol, high-density-lipoprotein (HDL)-cholesterol triacylglycerols. Between 7 11 28 32 complete 5 d collections made measurement neutral, acidic conjugated steroids. After HDL-cholesterol raised significantly all groups, but different extents. In comparison with diet-induced hypercholesterolaemia inhibited consuming beans, although maintained. Faecal by not from that 2. results suggest mechanism hypocholesterolaemic does involve increased hepatic bile acid synthesis thereby clearance via intestinal route.