Contribution of hGH20K variant to blood hGH response in sauna and exercise.

摘要: Exercise-induced increases in blood somatotropin (hGH) have always been considered terms of quantity the circulating molecules. Knowing that hypophysis can release several GH species, we investigated differential total hGH (hGHT) and main variant (hGH20K) molecules six trained male swimmers exposed to three different conditions known favor blood: 45 min − 70% maximum oxygen uptake $$(\dot V{\text{O}}_{{\text{2max}}} )$$ bicycling swimming, 20 sauna bathing. Based on binding specificity antibodies, hGH20K was isolated then assayed using Nichols immunoradiometric assay system. All experimental produced significant (P < 0.001) elevations hGHT hGH20K. In all cases, mean contribution relatively constant (11.9, SE 0.7%). Rises rectal temperature were not statistically related changes hGHT. This demonstration a elevation during bicycling, bathing hardly explain large differences responses reported literature under similar conditions.