Implications for KRAS status and EGFR-targeted therapies in metastatic CRC

作者: Nicola Normanno , Sabine Tejpar , Floriana Morgillo , Antonella De Luca , Eric Van Cutsem

DOI: 10.1038/NRCLINONC.2009.111

关键词:

摘要: … —occur in about 5–10% of CRC and are usually mutually exclusive with a KRAS mutation. … precursors of CRC. Moreover, KRAS mutations are maintained throughout CRC development…

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