A Network-Based Neurobiological Model of PTSD: Evidence From Structural and Functional Neuroimaging Studies

摘要: Although a fine-grained understanding of the neurobiology posttraumatic stress disorder (PTSD) is yet to be elucidated, last two decades have seen rapid growth in study PTSD using neuroimaging techniques. The current review summarizes important findings from functional and structural studies PTSD, by primarily focusing on their relevance towards an emerging network-based neurobiological model disorder. may characterized weakly connected hypoactive default mode network (DMN) central executive (CEN) that are putatively destabilized overactive hyperconnected salience (SN), which appears low threshold for perceived saliency, inefficient DMN-CEN modulation. There considerable evidence large-scale dysfunction PTSD. Nevertheless, several limitations gaps literature need addressed future research.