Defective Resection at DNA Double-Strand Breaks Leads to De Novo Telomere Formation and Enhances Gene Targeting
作者： Woo-Hyun Chung , Zhu Zhu , Alma Papusha , Anna Malkova , Grzegorz Ira
DOI: 10.1371/JOURNAL.PGEN.1000948
关键词:
摘要: … The formation of single-stranded DNA (ssDNA) at double-strand break (DSB) ends is … Here we estimated the length of ssDNA generated during DSB repair and analyzed the …
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Vincent Pennaneach, Christopher D. Putnam, Richard D. Kolodner, Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae. Molecular Microbiology. ,vol. 59, pp. 1357- 1368 ,(2006) , 10.1111/J.1365-2958.2006.05026.X
Kyungjae Myung, Clark Chen, Richard D. Kolodner, Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae Nature. ,vol. 411, pp. 1073- 1076 ,(2001) , 10.1038/35082608
Sairei So, Yuji Nomura, Noritaka Adachi, Yuki Kobayashi, Tamaki Hori, Yasuyuki Kurihara, Hideki Koyama, Enhanced gene targeting efficiency by siRNA that silences the expression of the Bloom syndrome gene in human cells Genes to Cells. ,vol. 11, pp. 363- 371 ,(2006) , 10.1111/J.1365-2443.2006.00944.X
Yun-Gui Yang, Tomas Lindahl, Deborah E. Barnes, Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease Cell. ,vol. 131, pp. 873- 886 ,(2007) , 10.1016/J.CELL.2007.10.017
Alessandro A. Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P. Jackson, Human CtIP promotes DNA end resection Nature. ,vol. 450, pp. 509- 514 ,(2007) , 10.1038/NATURE06337
Grzegorz Ira, Achille Pellicioli, Alitukiriza Balijja, Xuan Wang, Simona Fiorani, Walter Carotenuto, Giordano Liberi, Debra Bressan, Lihong Wan, Nancy M. Hollingsworth, James E. Haber, Marco Foiani, DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 Nature. ,vol. 431, pp. 1011- 1017 ,(2004) , 10.1038/NATURE02964
Serge Gravel, Michel Larrivee, Pascale Labrecque, Raymund J Wellinger, Yeast Ku as a Regulator of Chromosomal DNA End Structure Science. ,vol. 280, pp. 741- 744 ,(1998) , 10.1126/SCIENCE.280.5364.741
Christian Zierhut, John F X Diffley, Break dosage, cell cycle stage and DNA replication influence DNA double strand break response. The EMBO Journal. ,vol. 27, pp. 1875- 1885 ,(2008) , 10.1038/EMBOJ.2008.111
Eleni P. Mimitou, Lorraine S. Symington, Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing Nature. ,vol. 455, pp. 770- 774 ,(2008) , 10.1038/NATURE07312
Chuan-Jen Wang, Wing Lam, Scott Bussom, Hua-Mei Chang, Yung-Chi Cheng, TREX1 acts in degrading damaged DNA from drug-treated tumor cells. DNA Repair. ,vol. 8, pp. 1179- 1189 ,(2009) , 10.1016/J.DNAREP.2009.06.006