Studies on Histogenesis of the Gastric Carcinoma Using Minute Cancers

摘要: Summary Histopathologically, we examined 53 lesions, in 13 cases, of minute cancers measuring less than 5 mm the largest diameter, order to study histogenesis gastric cancer. Forty-four lesions four cases were undifferentiated adenocarcinoma, and nine differentiated adenocarcinoma. Cancer cells type confined lamina propria mucosa, especially near generative cell zone neck pit, had a tendency extend surface as size cancer increased. The surrounding mucosa was ordinary epithelia stomach without intestinal metaplasia. Atrophy pseudopyloric fundic glands seen at with inflammatory-cell infiltration. involve entire thickness by replacing pits. composed markedly intestinalized epithelia. And border between epithelial sharp. pyloric We conclude that both types carcinomas occur from pit. may originate stomach, penetrate basement membrane pit appear propria. On other hand, seem epithelium replace