Risk factors for pneumonia caused by multidrug-resistant Gram-negative bacilli among liver recipients.

摘要: Pneumonia caused by multidrug-resistant (MDR) Gram-negative bacilli is associated with a higher mortality rate. The appropriate empiric therapy based on the understanding of local etiology and MDR pattern. This study was to evaluate spectrum bacilli, rate, risk factors in 475 liver transplantation (LT) recipients. In first six months after LT, incidence bacterial pneumonia 21.3% (101/475). overall infectious during post-transplant month 80.2%. most frequent isolates were Enterobacteriaceae, Acinetobacter baumannii, Pseudomonas aeruginosa Staphylococcus aureus. accounted for 69.6% all pathogens. Of main 124 isolates, rate 58.9%. Four post-LT LT candidates grade II-IV encephalopathy (OR 2.275, 95%CI 1.249-4.124, p = 0.006), prolonged duration endotracheal intubation 8.224, 4.276-15.815, 0.013), tracheostomy 4.929, 1.099-18.308, 0.027) episode(s) reoperations 10.597, 3.726-30.134, < 0.001). pneumonia-related significantly than that because antibiotic-susceptible (45.6% vs. 11.4%, 0.010). Our data suggest common, severity underlying disease, mechanical ventilation upper abdominal surgery.