The Correlation between Troponin and Ferritin Serum Levels in the Patients with Major Beta-Thalassemia.

摘要: Background: Thalassemia is a hereditary hemoglobinopathy whose most common complication cardiac involvement which ends up in these patients’ death. Since troponin sensitive and specific marker for the detection of microinfarct, we studied relationship between ferritin serum levels early diagnosis patients. Materials Methods: This case-control study was performed on 80 patients, including 40 patients with major thalassemia normal echocardiography healthy volunteers ranging from 6 months to 16 years old. All children were examined eligible who not infected known heart disease, iron deficiency anemia, kidney diabetes, fever, systemic diseases enrolled into after obtaining written informed consents their parents. At 8:00 A.M. before breakfast, 5cc blood drawn children. After collecting samples, evaluated using ELISA electrokymonolonsense methods, respectively. The gathered data analyzed through SPSS statistical software (v. 20) T-test. Besides, P value<0.05 considered as statistically significant. Results: results revealed significant difference two groups regarding mean (P=0.045) (P=0.001). In this study, no correlation observed age BMI groups. Also, found level sex (P=0.264). Conclusions: increases independent ferritin; therefore, it can be used determine sub-clinical effects.