Cardiac disease in beta-thalassaemia major: Is it reversible?

摘要: Introduction: The aim of this study was to evaluate the spectrum cardiac Involvement and Its outcome in beta-thalassaemia major. Methods: There were 75 patients with a mean age 13.8 (+/- 5.5) years, whom 33 male 42 female. Clinical history, examination laboratory investigations assessed. Electrocardiograms, chest radiographs echocardiograms reviewed. Results: 44 had form left ventricular systolic dysfunction In 17, diastolic 22, pericardial effusion 12 pulmonary hypertension patients. With intense chelation therapy medications, condition 13 17 dysfunction, four 22 improved. Conclusion: Cardiac disease is common complication siderotic thalassaemia major It can be prevented regular chelation. This has shown improved function after therapy.