Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
作者： Isabelle Mercier , Hallgeir Rui , Richard G. Pestell , Michael P. Lisanti , Terence M. Williams
DOI: 10.2353/AJPATH.2006.060590
关键词:
摘要: … does not meet the classical criteria as a tumor suppressor protein (such as BRCA-1, Rb, or p53) because Cav-1 KO mice do not spontaneously develop mammary tumors. On the other …
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