Impact of TBI, PTSD, and hearing loss on tinnitus progression in a US Marine cohort

摘要: Introduction Mild TBI (TBI) is associated with up to a 75.7% incidence of tinnitus, and 33.0% tinnitus patients at the US Veterans Administration carry diagnosis post-traumatic stress syndrome (PTSD). Yet factors contributing new onset or exacerbation remain unclear. Materials methods Here we measure intermittent constant two time points ascertain whether pre-existing co-occurring traumatic brain injury (TBI), hearing loss, disorder (PTSD) predicts onset, lack recovery and/or worsening in 2,600 United States Marines who were assessed before after combat deployment. Results Ordinal regression revealed that deployment was likely continue (odds ratio [OR] = 28.62, 95% confidence interval [CI]: 9.84,83.26). Prior increased risk post-deployment (OR 4.95, CI: 2.97,8.27). Likelihood progression partial PTSD 2.39, 1.50,3.80) 1.59, 1.13,2.23), particularly for blast 2.01, 1.27,3.12) moderate severe 2.57, 1.46,4.51). Tinnitus also low frequency loss 1.94, 1.05,3.59), high 3.01, 1.91,4.76) across both ranges 5.73, 2.67,12.30). Conclusions Screening individual symptoms PTSD, TBI, may allow more focused treatment programs comorbid disorders. Identification those personnel vulnerable its direct acoustic protection risk.