Blood pressure after cardiac transplantation in childhood.

作者: John J. O’Sullivan , G. Derrick , J. Gray

DOI: 10.1016/J.HEALUN.2004.05.025

关键词:

摘要: Background There has been little formal study of blood pressure in children after cardiac transplantation. Methods Twenty-four-hour and clinical (BP) were measured 28 (>6 months transplantation) compared with a large amount normal data. Results Conventional (clinical) systolic BP (SBP) was elevated 9 (32.1%) (95% confidence interval [CI] 15.8 to 52.3), conventional diastolic (DBP) 5 (17.8%) CI 6.0 36.8). Mean 24-hour >97.5 percentile 2 (7.7%) 26 0.9 25.1) for SBP 7 (28.0%) 25 12.1 49.4) DBP. In comparison the control population, mean nighttime 8.9 mm Hg higher transplanted group 4.8 13.1), but daytime similar. day, night, DBP significantly patients. The decrease less than controls SBP, not measurement poorly predictive BP. significant association between interventricular septal thickness ( r = 0.35; p 0.01). associated 0.07; 0.20) correlated time since transplantation 0.42; 0.03 0.43; 0.04 DBP). Conclusions elevation is unexplained. possible important therapeutic implications predicted by measurement.

参考文章(14)
Kenneth G Zahka, Report of the Second Task Force on Blood Pressure Control in Children. Maryland medical journal. ,vol. 36, pp. 323- 325 ,(1987)
R F Wilson, B V Christensen, M T Olivari, A Simon, C W White, D D Laxson, Evidence for structural sympathetic reinnervation after orthotopic cardiac transplantation in humans Circulation. ,vol. 83, pp. 1210- 1220 ,(1991) , 10.1161/01.CIR.83.4.1210
J. J. O'sullivan, G. Derrick, P. E. Griggs, C. Wren, Validation of the Takeda 2421 ambulatory blood pressure monitor in children Journal of Medical Engineering & Technology. ,vol. 22, pp. 101- 105 ,(1998) , 10.3109/03091909809062474
J Sehested, E Happe, K Ishino, R Hetzer, U Schiessler, S Schifter, Diurnal variation in blood pressure in patients with biventricular assist devices and retained, nonpumping native hearts. Circulation. ,vol. 89, pp. 2601- 2604 ,(1994) , 10.1161/01.CIR.89.6.2601
H. Jorge Baluarte, Alan B. Gruskin, Julie R. Ingelfinger, Donald Stablein, Amir Tejani, Analysis of hypertension in children post renal transplantation —a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) Pediatric Nephrology. ,vol. 8, pp. 570- 573 ,(1994) , 10.1007/BF00858130
G Sigfússon, FJ Fricker, D Bernstein, LJ Addonizio, D Baum, DT Hsu, C Chin, SA Miller, GJ Boyle, J Miller, KS Lawrence, JF Douglas, BP Griffith, BA Reitz, RE Michler, EA Rose, SA. Webber, Long-term survivors of pediatric heart transplantation: A multicenter report of sixty-eight children who have survived longer than five years The Journal of Pediatrics. ,vol. 130, pp. 862- 871 ,(1997) , 10.1016/S0022-3476(97)70270-1
Ugo Giordano, Maria Chiara Matteucci, Armando Calzolari, Attilio Turchetta, Gianfranco Rizzoni, Bruce S. Alpert, Ambulatory blood pressure monitoring in children with aortic coarctation and kidney transplantation The Journal of Pediatrics. ,vol. 136, pp. 520- 523 ,(2000) , 10.1016/S0022-3476(00)90016-7
D.Scott Lim, Carlen A Gomez, Caren S Goldberg, Dennis C Crowley, Albert P Rocchini, John R Charpie, Systemic arterial pressure and brachial arterial flow-mediated dilatation in young cardiac transplant recipients. American Journal of Cardiology. ,vol. 90, pp. 1035- 1037 ,(2002) , 10.1016/S0002-9149(02)02698-X
David O. McGregor, Claire Olsson, and Kelvin L. Lynn, Autonomic dysfunction and ambulatory blood pressure in renal transplant recipients. Transplantation. ,vol. 71, pp. 1277- 1281 ,(2001) , 10.1097/00007890-200105150-00016
Jens Sehested, Frank Thomas, Martin Thom, Søren Schifter, Vera Regitz, Søren Sheikh, Wolfgang Oelkers, Ülo Palm, Wolfgang Meyer-Sabellek, Roland Hetzer, Level and diurnal variations of hormones of interest to the cardiovascular system in patients with heart transplants. American Journal of Cardiology. ,vol. 69, pp. 397- 402 ,(1992) , 10.1016/0002-9149(92)90241-P