Predictive and prognostic value of metabolic tumour volume and total lesion glycolysis in solid tumours

摘要: Data available in patients suffering from squamous cell carcinoma of the head and neck, lung carcinoma, oesophageal gynaecological malignancies suggest that metabolic tumour volume to a lesser extent total lesion glycolysis have potential become valuable imaging human solid tumours as prognostic biomarkers for short- intermediate-term survival outcomes, adding value clinical staging, assessment response treatment with neoadjuvant concurrent chemotherapy, optimization; example, based on early using changes over time, it might be possible select who require more aggressive improve their outcome. Prospective studies enrolling consecutive patients, adopting standardized protocols FDG PET acquisition processing, adjusting confounders analysis (tumour size origin) determining optimal methodology determination these novel markers are mandatory.