Plasma neutrophil gelatinase associated lipocalin (NGAL) is associated with kidney function in uraemic patients before and after kidney transplantation

作者: Nils E Magnusson , Mads Hornum , Kaj Anker Jørgensen , Jesper Melchior Hansen , Claus Bistrup

DOI: 10.1186/1471-2369-13-8

关键词:

摘要: Neutrophil gelatinase associated lipocalin (NGAL) is a biomarker of kidney injury. We examined plasma levels NGAL in cohort 57 allograft recipients (Tx group, 39 ± 13 years), uraemic group 40 patients remaining on the waiting list (47 11 years) and control 14 healthy subjects matched for age, sex body mass index (BMI). The graft were studied at baseline before transplantation 3 12 months after months.

参考文章(45)
Donald W. Cockcroft, Henry Gault, Prediction of Creatinine Clearance from Serum Creatinine Nephron. ,vol. 16, pp. 31- 41 ,(1976) , 10.1159/000180580
L. Kjeldsen, A.H. Johnsen, H. Sengeløv, N. Borregaard, Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase Journal of Biological Chemistry. ,vol. 268, pp. 10425- 10432 ,(1993) , 10.1016/S0021-9258(18)82217-7
J Forsblad, Anders Gottsäter, Lennart Jacobsson, K Persson, Folke Lindgärde, Clinical manifestations of atherosclerosis in an elderly population are related to plasma neopterin, NGAL and endothelin-1, but not to Chlamydia pneumoniae serology. International Angiology. ,vol. 21, pp. 173- 179 ,(2002)
Ole E. Sørensen, Jack B. Cowland, Kim Theilgaard-Mönch, Lide Liu, Tomas Ganz, Niels Borregaard, Wound Healing and Expression of Antimicrobial Peptides/Polypeptides in Human Keratinocytes, a Consequence of Common Growth Factors Journal of Immunology. ,vol. 170, pp. 5583- 5589 ,(2003) , 10.4049/JIMMUNOL.170.11.5583
L. Sevéus, Kawa Amin, Christer G. B. Peterson, Godfried M. Roomans, Per Venge, Human neutrophil lipocalin (HNL) is a specific granule constituent of the neutrophil granulocyte. Studies in bronchial and lung parenchymal tissue and peripheral blood cells Histochemistry and Cell Biology. ,vol. 107, pp. 423- 432 ,(1997) , 10.1007/S004180050129
Derek S. Wheeler, Prasad Devarajan, Qing Ma, Kelli Harmon, Marie Monaco, Natalie Cvijanovich, Hector R. Wong, Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Critical Care Medicine. ,vol. 36, pp. 1297- 1303 ,(2008) , 10.1097/CCM.0B013E318169245A
Constantinos Giaginis, Athina Zira, Athanasios Katsargyris, Chris Klonaris, Stamatios Theocharis, Clinical implication of plasma neutrophil gelatinase-associated lipocalin (NGAL) concentrations in patients with advanced carotid atherosclerosis Clinical Chemistry and Laboratory Medicine. ,vol. 48, pp. 1035- 1041 ,(2010) , 10.1515/CCLM.2010.211
Soledad Garcia de Vinuesa, Mayra Ortega, Patricia Martinez, Marian Goicoechea, Francisco Gomez Campdera, Jose Luño, Subclinical peripheral arterial disease in patients with chronic kidney disease: Prevalence and related risk factors Kidney International. ,vol. 67, pp. S44- S47 ,(2005) , 10.1111/J.1523-1755.2005.09310.X
Gebhard Wagener, Michael Jan, Mihwa Kim, Kiyoshi Mori, Jonathan M. Barasch, Robert N. Sladen, H Thomas Lee, Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology. ,vol. 105, pp. 485- 491 ,(2006) , 10.1097/00000542-200609000-00011
R. C. Patel, D. Lange, W. J. McConathy, Y. C. Patel, S. C. Patel, Probing the structure of the ligand binding cavity of lipocalins by fluorescence spectroscopy. Protein Engineering. ,vol. 10, pp. 621- 625 ,(1997) , 10.1093/PROTEIN/10.6.621